NT-proBNP: N-terminal pro hormone of brain natriuretic peptide (pg/ml)

NYHA: New York Heart Association functional class 

• I: No symptoms and no limitation in ordinary physical activity, e.g. shortness of breath when walking, climbing stairs
  
• II: Mild symptoms (mild shortness of breath and/or angina) and slight limitation during ordinary activity
  
• III: Marked limitation in activity due to symptoms, even during less-than-ordinary activity, e.g. walking short distances
• IV: Severe limitations. Experiences symptoms even while at rest. Mostly bedbound patients

Hemoglobin: Baseline hemoglobin levels (g/dl)

TAPSE: Tricuspid annular plane systolic excursion (mm)

• Measured by M-mode with the cursor optimally aligned along the direction of the tricuspid lateral annulus in the apical four-chamber view

Age: Age at the time of M-TEER (years)

eGFR: Estimated glomerular filtration rate (ml/min)

RA Area: Right atrial area (cm²)

• Assessed in an apical four chamber view at end-systole
  

sPAP: Systolic pulmonary artery pressure (mmHg)

• Echocardiographically assessed by addition of estimated RA pressure and maximum systolic tricuspid pressure gradient
  
• Inferior vena cava (IVC) diameter < 2.1cm that collapses >50% with a sniff suggests normal RA pressure of 3 mmHg, whereas IVC diameter > 2.1cm that collapses < 50% with a sniff suggests high RA pressure of 15 mmHg
  

LVEDV: Left ventricular end-diastolic volume (ml)

• Assessed by Simpsons biplane method
  
• Volume measurements are usually based on tracings of the blood- tissue interface in the apical four- and two- chamber views. At the mitral valve level, the contour is closed by connecting the two opposite sections of the mitral ring with a straight line. LV length is defined as the distance between the middle of this line and the most distant point of the LV contour.
  

TR grade: TR severity grade using a four grade scale

• 0+: None
  
• 1+: Mild
• 2+: Moderate
• 3+: Severe
• 4+: Massive/Torrential

Diabetes Mellitus: Either dietary treated, on oral anti diabetics or insulin dependent

RVmid diameter: Mid-ventricular diameter of the right ventricle (mm)

• Diameter of the right ventricle at a mid-ventricular level at end-diastole
  

MR EROA: Mitral regurgitation effective regurgitant orifice area (cm²)

• As derived from the proximal isovelocity surface area method
  

BMI: Body mass index (kg/cm²)

LA volume: Left atrial volume (ml)

• Assessed by a biplane approach at end-systole

LVEF: Left ventricular ejection fraction (%)

• As derived from Simpsons Biplane method
  

Triple GDMT: Application of a triple guideline directed medical treatment

• Application of renin-angiotensin system inhibitors, mineralocorticoid-receptor antagonists, and beta blockers
  

COPD: Chronic obstructive pulmonary disease